Additional research articles are available

by clicking on the Titles below: 

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"The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy

with 3-Bromopyruvate"

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"Mitochondrial bound type II hexokinase: a key player in the growth and
survival of many cancers and an ideal prospect for therapeutic intervention"

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"Hexokinase II: Cancer’s double-edged sword acting as both facilitator and
gatekeeper of malignancy when bound to mitochondria"

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"A translational study “case report” on the small molecule
“energy blocker” 3-bromopyruvate (3BP) as a potent
anticancer agent: from bench side to bedside"

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"Hexokinase-2 bound to mitochondria: Cancer’s stygian link to the
“Warburg effect” and a pivotal target for effective therapy"

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"The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies"

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"3-Bromopyruvate: A novel antifungal agent against the human pathogen
Cryptococcus neoformans"

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"The anticancer agent 3-bromopyruvate: a simple but powerful
molecule taken from the lab to the bedside"

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"Transport and cytotoxicity of the anticancer drug 3-bromopyruvate

in the yeast Saccharomyces cerevisiae"

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"Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections

as well as multiple myeloma"

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"Killing multiple myeloma cells with the small molecule
3-bromopyruvate: implications for therapy"

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"Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate"

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"Transport of 3-Bromopyruvate across the human erythrocyte membrane" 

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ResearchGate.net Scientific Contributions by Dr. Ko

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