Scientific Research Publications

November 14, 2018

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Breakthrough Study


Anti-cancer Agent

Glucose Catabolism in

Rat Liver Tumors

Targeting Cancer Cell's Power Plants with 3BP

Additional research articles are available
by clicking on the Titles below: 

"The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer:
Targets for Effective Therapy with 3-Bromopyruvate"

"Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers
and an ideal prospect for therapeutic intervention"

"Hexokinase II: Cancer’s double-edged sword acting as both facilitator and
gatekeeper of malignancy when bound to mitochondria"

"A translational study “case report” on the small molecule “energy blocker” 3-bromopyruvate (3BP) as
a potent anticancer agent: from bench side to bedside"

"Hexokinase-2 bound to mitochondria: Cancer’s stygian link to the “Warburg effect”
and a pivotal target for effective therapy"

"The pivotal roles of mitochondria in cancer: Warburg and beyond and
encouraging prospects for effective therapies"

"3-Bromopyruvate: A novel antifungal agent against the human pathogen Cryptococcus neoformans"

"The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside"

"Transport and cytotoxicity of the anticancer drug 3-bromopyruvatein the yeast Saccharomyces cerevisiae"

"Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma"

"Killing multiple myeloma cells with the small molecule3-bromopyruvate: implications for therapy"

"Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate"

"Transport of 3-Bromopyruvate across the human erythrocyte membrane" 

Find More Studies Here Scientific Contributions by Dr. Ko